Yes, they did but we don't have the official and exact view of how and why it happen... The idea is that, they did have sex and that brought them the tension they have right now...
See all the good stuff that can come out when you had fun for just one night?
I think they had but only House refers to. We saw in "Joy to the world" that Cuddy understood feelings of Natalie about being a looser in college. Maybe, she chose him at the time as a challenge and a way to have madami self confidence. House should already have a "reputation".
yes they did....and the way they first came to knowing each other is that cuddy signed up 4 a class that house was in because still then she thought he was a interesting maniac....and that led to sex in college....and can be confermed in the ep. "top secret"
